It's in the details. M I N E R A L G U I D E Reference Guide to Jost Mineral Compounds
Additional factors that play a role in mineral
of mineral compounds that are used in the
selection are referenced at end of the guide.
nutritional supplement, clinical nutrition,
pharmaceutical and food markets. This reference
Generally, the mineral salts in each chart are
guide highlights several key points to consider
arranged by descending solubility and increasing
when formulating a product: Solubility, Metal Content and Taste.
Jost’s products are manufactured under cGMP
The mineral salts discussed in the guide include
guidelines in our FDA registered facility in
Ca, Cu, Fe, Mg, Mn, and Zn. Also included in
St. Louis, Missouri. Our products are Kosher/
the guide are K and Na. The Mineral Guide
HALAL certified, non-GMO, non-allergenic,
BSE/TSE free, and free of residual solvents.
JOST CHEMICAL CO. U.S.A. 8150 Lackland Rd. St. Louis, MO 63114 (USA) n Tel: +1 (314) 428-4300 n Fax: +1 (314) 428-4366 Europe Rue de Perwez, 108A B-5300 ANDENNE (Belgium) n Tel: +32 85 23 17 11 n Fax: +32 85 23 36 57 www.jostchemical.com Solubility %2,3 Content % Calcium Gluconate Anhydrous Calcium Lactate Anhydrous Calcium Fumarate Trihydrate Calcium Fumarate Anhydrous Calcium Phosphate Monobasic Calcium Citrate Malate Calcium Malate Anhydrous Calcium Hydroxide Calcium Magnesium Citrate Calcium Citrate Tetrahydrate Calcium Succinate Monohydrate Calcium Phosphate Tribasic Anhydrous (TCP) Calcium Carbonate Anhydrous Calcium Phosphate Dibasic Anhydrous (DCPA)
1. Generally arranged by descending solubility and increasing metal content.
2. Solubility in percent. Superscript is temperature; if no superscript, 25°C.
3. CRC Handbook and Merck Index are the main sources of this information.
4. Taste profiles developed by Jost personnel and are subjective. JOST CHEMICAL CO. U.S.A. 8150 Lackland Rd. St. Louis, MO 63114 (USA) n Tel: +1 (314) 428-4300 n Fax: +1 (314) 428-4366 Europe Rue de Perwez, 108A B-5300 ANDENNE (Belgium) n Tel: +32 85 23 17 11 n Fax: +32 85 23 36 57 www.jostchemical.com Solubility %2,3 Content % Copper Sulfate Pentahydrate Copper Gluconate Anhydrous Copper Sulfate Anhydrous Copper Citrate Hemi-Trihydrate Basic Copper Carbonate Copper Oxide Anhydrous
1. Generally arranged by descending solubility and increasing metal content.
2. Solubility in percent. Superscript is temperature; if no superscript, 25°C.
3. CRC Handbook and Merck Index are the main sources of this information.
4. Taste profiles developed by Jost personnel and are subjective. JOST CHEMICAL CO. U.S.A. 8150 Lackland Rd. St. Louis, MO 63114 (USA) n Tel: +1 (314) 428-4300 n Fax: +1 (314) 428-4366 Europe Rue de Perwez, 108A B-5300 ANDENNE (Belgium) n Tel: +32 85 23 17 11 n Fax: +32 85 23 36 57 www.jostchemical.com Solubility %2,3 Iron Content % Ferric Ammonium Citrate Brown Ferrous Ammonium Sulfate Hexahydrate Ferrous Gluconate Dihydrate Ferrous Lactate Dihydrate Ferrous Fumarate Anhydrous Ferric Phosphate Hydrate Ferric Pyrophosphate Ferrous Citrate Dibasic Monohydrate Ferric Citrate x-Hydrate
1. Generally arranged by descending solubility and increasing metal content.
2. Solubility in percent. Superscript is temperature; if no superscript, 25°C.
3. CRC Handbook and Merck Index are the main sources of this information.
4. Taste profiles developed by Jost personnel and are subjective. JOST CHEMICAL CO. U.S.A. 8150 Lackland Rd. St. Louis, MO 63114 (USA) n Tel: +1 (314) 428-4300 n Fax: +1 (314) 428-4366 Europe Rue de Perwez, 108A B-5300 ANDENNE (Belgium) n Tel: +32 85 23 17 11 n Fax: +32 85 23 36 57 www.jostchemical.com Magnesium Magnesium Solubility %2,3 Content % Magnesium Ascorbate x-Hydrate Magnesium Sulfate Heptahydrate Magnesium Aspartate Monobasic Dihydrate Magnesium Sulfate Dried Magnesium Citrate Tribasic Anhydrous7 Magnesium Aspartate Dibasic Anhydrous Magnesium Gluconate Hydrate5 Magnesium Lactate Anhydrous6 Magnesium Lactate Dihydrate Magnesium Malate Trihydrate Magnesium Citrate Tribasic x-Hydrate Magnesium Phosphate Dibasic Trihydrate Magnesium Phosphate Tribasic Pentahydrate
1. Generally arranged by descending solubility and increasing metal content.
5. Jost’s Magnesium Gluconate is typically a dihydrate.
2. Solubility in percent. Superscript is temperature; if no superscript, 25°C.
6. Calculated based on dihydrate solubility.
3. CRC Handbook and Merck Index are the main sources of this information.
7. After initial dissolution, anhydrous Magnesium Citrate
4. Taste profiles developed by Jost personnel and are subjective.
reprecipitates as the hydrated form. JOST CHEMICAL CO. U.S.A. 8150 Lackland Rd. St. Louis, MO 63114 (USA) n Tel: +1 (314) 428-4300 n Fax: +1 (314) 428-4366 Europe Rue de Perwez, 108A B-5300 ANDENNE (Belgium) n Tel: +32 85 23 17 11 n Fax: +32 85 23 36 57 www.jostchemical.com Manganese Manganese Solubility %2,3 Content % Manganese Sulfate Monohydrate Manganese Gluconate Dihydrate Manganese Lactate Dihydrate Manganese Citrate Decahydrate Manganese Ascorbate Dihydrate
1. Generally arranged by descending solubility and increasing metal content.
2. Solubility in percent. Superscript is temperature; if no superscript, 25°C.
3. CRC Handbook and Merck Index are the main sources of this information.
4. Taste profiles developed by Jost personnel and are subjective. JOST CHEMICAL CO. U.S.A. 8150 Lackland Rd. St. Louis, MO 63114 (USA) n Tel: +1 (314) 428-4300 n Fax: +1 (314) 428-4366 Europe Rue de Perwez, 108A B-5300 ANDENNE (Belgium) n Tel: +32 85 23 17 11 n Fax: +32 85 23 36 57 www.jostchemical.com Potassium Potassium Solubility %2,3 Content % Di-Potassium Citrate Anhydrous Potassium Gluconate Anhydrous Potassium Phosphate Dibasic Potassium Carbonate Anhydrous Potassium Phosphate Monobasic Potassium Nitrate Potassium Sulfate
1. Generally arranged by descending solubility and increasing metal content.
2. Solubility in percent. Superscript is temperature; if no superscript, 25°C.
3. CRC Handbook and Merck Index are the main sources of this information.
4. Taste profiles developed by Jost personnel and are subjective. JOST CHEMICAL CO. U.S.A. 8150 Lackland Rd. St. Louis, MO 63114 (USA) n Tel: +1 (314) 428-4300 n Fax: +1 (314) 428-4366 Europe Rue de Perwez, 108A B-5300 ANDENNE (Belgium) n Tel: +32 85 23 17 11 n Fax: +32 85 23 36 57 www.jostchemical.com Solubility %2,3 Content % Sodium Phosphate Dibasic Anhydrous Sodium Caprylate Sodium Acetate Trihydrate Sodium Nitrate Anhydrous Sodium Phosphate Tribasic Dodecahydrate Sodium Phosphate Monobasic Anhydrous Sodium Phosphate Monobasic Monohydrate Sodium Sulfate Decahydrate
1. Generally arranged by descending solubility and increasing metal content.
2. Solubility in percent. Superscript is temperature; if no superscript, 25°C.
3. CRC Handbook and Merck Index are the main sources of this information.
4. Taste profiles developed by Jost personnel and are subjective. JOST CHEMICAL CO. U.S.A. 8150 Lackland Rd. St. Louis, MO 63114 (USA) n Tel: +1 (314) 428-4300 n Fax: +1 (314) 428-4366 Europe Rue de Perwez, 108A B-5300 ANDENNE (Belgium) n Tel: +32 85 23 17 11 n Fax: +32 85 23 36 57 www.jostchemical.com Sodium (continued) Solubility %2,3 Content % Sodium Phosphate Dibasic Heptahydrate Sodium Phosphate Dibasic Dihydrate Sodium Succinate Anhydrous Sodium Bisulfate Monohydrate Sodium Pyrophosphate Dodecahydrate Sodium Sulfate Anhydrous Sodium Carbonate Monohydrate Sodium Carbonate Anhydrous
1. Generally arranged by descending solubility and increasing metal content.
2. Solubility in percent. Superscript is temperature; if no superscript, 25°C.
3. CRC Handbook and Merck Index are the main sources of this information.
4. Taste profiles developed by Jost personnel and are subjective. JOST CHEMICAL CO. U.S.A. 8150 Lackland Rd. St. Louis, MO 63114 (USA) n Tel: +1 (314) 428-4300 n Fax: +1 (314) 428-4366 Europe Rue de Perwez, 108A B-5300 ANDENNE (Belgium) n Tel: +32 85 23 17 11 n Fax: +32 85 23 36 57 www.jostchemical.com Solubility %2,3 Zinc Content % Zinc Ascorbate Zinc Gluconate Hydrate5 Zinc Lactate Dihydrate Zinc Citrate Trihydrate Zinc Citrate Dihydrate Zinc Phosphate Tribasic Tetrahydrate Zinc Oxide Low Pb
1. Generally arranged by descending solubility and increasing metal content.
2. Solubility in percent. Superscript is temperature; if no superscript, 25°C.
3. CRC Handbook and Merck Index are the main sources of this information.
4. Taste profiles developed by Jost personnel and are subjective.
5. Jost’s Zinc Gluconate is typically a dihydrate. JOST CHEMICAL CO. U.S.A. 8150 Lackland Rd. St. Louis, MO 63114 (USA) n Tel: +1 (314) 428-4300 n Fax: +1 (314) 428-4366 Europe Rue de Perwez, 108A B-5300 ANDENNE (Belgium) n Tel: +32 85 23 17 11 n Fax: +32 85 23 36 57 www.jostchemical.com JOSTCOTE® Microencapsulated Products Solubility %2,3 Mineral Content % JOSTCOTE® Microencapsulated Copper Gluconate 20% JOSTCOTE® Microencapsulated Ferrous Fumarate 60% JOSTCOTE® Microencapsulated Ferrous Sulfate Dried 60% JOSTCOTE® Microencapsulated Magnesium Oxide 40% JOSTCOTE® Microencapsulated Manganese Sulfate 50% JOSTCOTE® Microencapsulated Reduced Iron 70% JOSTCOTE® Microencapsulated Zinc Oxide 50%
1. Generally arranged by descending solubility and increasing metal content.
2. Solubility in percent. Superscript is temperature; if no superscript, 25°C.
3. CRC Handbook and Merck Index are the main sources of this information.
4. Taste profiles developed by Jost personnel and are subjective. JOST CHEMICAL CO. U.S.A. 8150 Lackland Rd. St. Louis, MO 63114 (USA) n Tel: +1 (314) 428-4300 n Fax: +1 (314) 428-4366 Europe Rue de Perwez, 108A B-5300 ANDENNE (Belgium) n Tel: +32 85 23 17 11 n Fax: +32 85 23 36 57 www.jostchemical.com Categories to Consider When Choosing Mineral Compounds Animal Origin GMO-Origin Monographs Price and Production Costs
For political and health reasons, concern
Mineral content per price can be a clear
animal products come into our facility. Bioavailability
suppliers use the term “Purified” to
Residual Solvents Heavy Metal Content
is available. Jost defines “Purified” as
meeting specifications that are equivalent
Bulk Density Shelf Life/Retest Date
For processing reasons, the bulk density
Nutritional Claims
Jost ensures our products are stable up to
may dictate the choice of the compound.
Many claims in the nutritional supplement
a specified retest date when the product is
Interaction with Other Molecules
stored in the original, unopened container
Some salts can be strong oxidizing agents
assurance that the requisite systems and
Solubility
Odor may reflect the raw material quality
Solubility plays a key role, especially for
consistency, safety, and traceability from
raw material receipt to finished product
Kosher or HALAL Certification Particle Size
in solid dosage process controls, taste,
Mineral Content
solubility concerns. If a salt is insoluble
Tolerance
Mineral content is provided as a % range
an ultrafine particle size can help keep
Effectiveness
to know a compound’s “as-is” mineral
Particle Size Consistency USP, NF, FCC, EP, ACS, Custom
simply blends and not fully reacted thus
inhibiting their stability in formulations.
determine which grade will be preferred. JOST CHEMICAL CO. U.S.A. 8150 Lackland Rd. St. Louis, MO 63114 (USA) n Tel: +1 (314) 428-4300 n Fax: +1 (314) 428-4366 Europe Rue de Perwez, 108A B-5300 ANDENNE (Belgium) n Tel: +32 85 23 17 11 n Fax: +32 85 23 36 57 www.jostchemical.com It's in the details. JOST CHEMICAL CO. U.S.A. 8150 Lackland Rd. St. Louis, MO 63114 (USA) n Tel: +1 (314) 428-4300 n Fax: +1 (314) 428-4366 Europe Rue de Perwez, 108A B-5300 ANDENNE (Belgium) n Tel: +32 85 23 17 11 n Fax: +32 85 23 36 57 www.jostchemical.com
RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED TRIAL OF ORAL ALBUTEROL IN INFANTS WITH MILD-TO-MODERATE ACUTE VIRAL BRONCHIOLITIS HEMA PATEL, MD, MSC, SERGE GOUIN, MDCM, AND ROBERT W. PLATT, MSC, MS, PHD Objective To determine whether oral albuterol is effective in reducing symptomatology of acute viral bronchiolitis in infants with mild-to-moderate illness. Study design In a randomiz
220370026_3.qxp 13.12.2010 10:05 Uhr Seite 1 How to Use Nitrolingual® Pumpspray Pumpspray Before using this product for the first 5. Press the button firmly with the forefinger to (nitroglycerin lingual spray) time, the pump must be sprayed 5 times release the spray onto or under the tongue. 400 mcg per spray, 60 or 200 Metered Sprays P into the air (this is kn
It's in the details.