Flu newsletter

Eye on Influenza
January 26, 2007
Volume 3, Issue 9
Orange County Health Care Agency, Epidemiology & Assessment, 1719 W. 17th St. Santa Ana, CA 92706, (714) 834-8180 Influenza activity has increased in Orange County. Consider influenza in your patients presenting with fever and/or respiratory symptoms. Several types of influenza testing are available; see http://www.cdc.gov/flu/professionals/diagnosis/labprocedures.htm for more information.
• DHHS awards contracts totalling $132.5 million to three companies to develop H5N1 vaccines using adjuvants: Because adjuvants can be used to boost the immune system’s response to a vaccine, the use of adjuvants may expand vaccine supplies during a pandemic. For more info, please visit: http://www.hhs.gov/news/press/2007pres/20070117a.html. • Reduced susceptibility to oseltamivir (Tamiflu) in 2 H5N1 cases in Egypt: Two patients from the same household were infected with an H5N1 strain that had “moderately reduced susceptibility” to Tamiflu. Because there is no evidence that Tamiflu-resistant strains are spreading in Egypt or elsewhere, Tamiflu is still recommended as the first-line drug for treatment of H5N1 infection. For more info: http://www.cidrap.umn.edu/cidrap/content/influenza/avianflu/news/jan1807tamiflu.html. For WHO guidelines on treatment and prophylaxis of H5N1, see http://www.who.int/csr/disease/avian_influenza/guidelines/pharmamanagement/en/index.html. Reported Influenza Cases by Type
Orange County
Orange County, 2006-2007 Influenza Season
• In the past 2 weeks, 38 new influenza cases (32 A, 4 B & 2 A/B unspecified) were reported. Of the 56 total this season; 46 unspecified. 41 (73%) were reported from hospitals and 15 (27%) were from ILI sentinel sites. Of the 24 subtyped flu A Number Reported Flu
influenza A viruses have been strain-typed 40 41 42 43 44 45 46 47 48 49 50 51 52 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 Disease Week and Month
Avian Influenza Update
California and USA
• Additional H5N1 avian outbreaks have been reported • California reported regional influenza in Hungary, Japan, Thailand, and Vietnam. activity during week 3. Nationally, 81.5% of • 269 human H5N1 cases have been confirmed in influenza detections were A; 18.5% were B. Azerbaijan (8), Cambodia (6), China (22), Djibouti (1), 92% of subtyped A viruses were A (H1); 8% Egypt (19)*, Indonesia (80)*, Iraq (3), Thailand (25), Turkey (12), and Vietnam (93), and have resulted in 163 (61%) deaths. H5N1-infected birds have been Caledonia/20/99-like.** Both A (H3) viruses reported in multiple areas in Asia, Africa and Europe. For a list of H5N1-affected countries, see like.** Of B viruses characterized, 67% were http://www.ochealthinfo.com/epi/af/index.htm. *New reported case(s) since January 12nd. B/Yamagata lineage. 52% of the B/Victoria • Please contact OC Epidemiology immediately at 714- 834-8180 to report any suspect avian influenza cases.
**Components of the 2006-2007 US flu vaccine:
• A (H1N1): A/New Caledonia/20/99-like OC: http://www.ochealthinfo.com/epi/flu/surveillance.htm • B: B/Malaysia/2506/2004-like (equal to CA: http://www.dhs.ca.gov/ps/dcdc/VRDL/html/FLU/Fluintro.htm CDC: http://www.cdc.gov/flu/weekly/; HHS: http://www.pandemicflu.gov/ If you have any comments about the flyer, contact Pamela Roa Hipp or Alina Burgi at (714) 834-8180. To receive this newsletter by email, please contact us at [email protected].

Source: http://www.chapmanmedicalcenter.com/healthresources/FluNews/FluFlyer-9-4-07.pdf