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metoprolol, propranolol), digoxin, cyclosporine, cyclophosphamide, tamoxifen, etoposide, paclitaxel, anti-seizure drugs (e.g., carbamazepine, phenytoin), diltiazem, nifedipine, tacrolimus, sirolimus, tricyclic antidepressants (e.g., amitriptyline, nortriptlyline). Low-dose aspirin (usually 81-325 mg per day) for heart attack or stroke prevention should be continued unless your doctor instructs you otherwise. Aspirin is similar to NSAID drugs, and can increase the risk of bleeding in combination with this medication. RARE SIDE EFFECTS: In very rare patients have side effects like black stools,
"coffee ground" vomit, easy bruising / bleeding.
PRECAUTIONS: When orally taken ADEPRESS CAPSULES may cause sun
sensitivity ("sunburn") reactions, so take help to use sunscreen and wear protective
clothing if are affected. ADEPRESS CAPSULES not recommended for use during
pregnancy and breast-feeding.
OVERDOSE: If overdose is suspected, discontinue the medicine for minimum 24
hours, drink plenty of plain water and contact the physician.
MISSED DOSE: If miss a dose, use it as soon as remember. If it is near the time of
the next dose, skip the missed dose and resume usual dosing schedule. Do not
double the dose to catch up.
PACKING: Approximate dosage size is 650 mg, active ingredient is 300 mg and
350 mg is excipients.
MANUFACTURER: Origna Laboratories
ADEPRESS CAPSULES contains Hypericum perforatum extracts (St. John's wort)
HPE 300 mg. This ingredient has been used for centuries to medically treat mental
disorders such as depression and anxiety. It has effects as anti-inflammatory,
antiseptic, and astringent. The major components in extract of Hypericum
perforatum (St. John's wort) has a beneficial effect on metabolism and bile secretion
and can positively affect mood; it will stimulate appetite, improve circulation and
have a general anti-inflammatory effect. Hypericum perforatum (St. John's wort)
extract can ease the symptoms of anxiety and depression, alleviate stress, promote
sleep, boost energy and relieve Premenstrual syndrome (PMS) OR Premenstrual
tension PMT symptoms.
INGREDIENTS: Hypericum perforatum (St. John's wort) Extract HPE 300mg
INDICATIONS: Depressive disorder (mild-to-moderate) Somatoform disorders,
Attention deficit hyperactivity disorder, Depression (Adults & children) Helps in
Nerve pain & As Nerve tonic, Hypochondriasis, Fatigue, Sleep disorders. Treating
wounds and for allaying the pain of contusions. . It helps to Premenstrual syndrome
PMS OR Premenstrual tension.
ADVERSE EFFECTS AND DRUG INTERACTIONS:
ADEPRESS CAPSULES is generally well tolerated, with an adverse effect profile
similar to placebo. The most common adverse effects reported are gastrointestinal
symptoms, dizziness, confusion, tiredness and sedation.
ADEPRESS CAPSULES may rarely cause photosensitivity. This can lead to visual
sensitivity to light and to sunburns in situations that would not normally cause them.
Related to this, recent studies concluded that the extract reacts with light, both
visible and ultraviolet, to produce free radicals, molecules that can damage the cells
of the body. These can react with vital proteins in the eye which, if damaged,
precipitate out causing cataracts. Women who use the contraceptive implant
Implanon are advised not to take ADEPRESS CAPSULES as it reduces the
implant's effectiveness. ADEPRESS CAPSULES should not use with the drugs
used to treat HIV infection such as protease inhibitors (e.g., indinavir) and
nonnucleoside reverse transcriptase inhibitors (NNRTI's such as delavirdine,
efavirenz, nevirapine), other drugs which can cause bleeding/bruising (e.g.,
thrombolytic drugs such as TPA, anticoagulants such as heparin or warfarin,
antiplatelet drugs including NSAIDs such as ibuprofen), beta-blockers (e.g.,

Source: http://www.unimedpharm.com/adepress.pdf