P A T I E N T I N F O R M A T I O N S H E E T Research has shown that imbalances of Oestrogen and Progesterone can contribute to osteoporosis, breastcancer, infertility and cardiovascular disease. In response to ageing, stress and other environmentalantagonists, hormone production and utilisation can be significantly impaired.The monthly fluctuation in Oestradiol and Progesterone plays a vital role in shaping the course of themenstrual cycle. Prior to menstruation, an imbalance of Progesterone and Oestrogen can produce physicaland emotional discomfort for women - causing PMS(loss of sex drive, appetite, mood and disturbed sleep patterns).
Another hormone manufactured by women, albeit in smaller quantities than in men, is testosterone. A deficiency of testosterone is
known to produce a decline in libido and a decreased overall sense of wel being in women. Elevated levels of testosterone are
frequently seen in women with Polycystic Ovarian Syndrome, which accounts for an increase in certain features
Anyone suffering from the following should consider having the female hormone panel: • Migraines • Irregular menstrual cycle • Hot flushes • Infertility • Water retention • Menopause • Endometriosis and PCOS • Loss of skin elasticity • High stress levels • Loss of lean body mass • Osteoporosis • Poor muscle and bone development • Decreased general wellbeing • Fatigue • Loss of motivation and drive • Sleep disorders • Excess hair in male distribution areas • Anxiety/depression • Hair loss • Loss of libido • Prone to acne How does the test work?
The Female Hormone Panel measures levels of Progesterone and Oestradiol over 28 days, using 12 saliva
samples. This test also assesses testosterone levels. Collection of hormones in saliva is a convenient non-
invasive and stress free procedure. In addition, saliva samples reveal critical information about hormones as,
unlike blood samples, they represent the free, bio-available fraction of the hormone.
C O M P R E H E N S I V E F E M A L E H O R M O N E PA N E L
The Comprehensive Female Hormone Panel includes the female hormone panel as detailed aboveplus a melatonin profile and an adrenal stress index test.
Melatonin is another hormone, which plays a vital role in the regulation of various hormones according to the natural daily cycle. It
helps to regulate body temperature, influences female reproductive hormones and cardiovascular function. It functions as a potent
antioxidant and enhances the immune system by stimulating natural killer cells. Its release is stimulated by dark and suppressed by
light. It is produced in abundance before puberty, but declines steadily after that until old age, when virtually none is produced.
Stress can directly affect the reproductive system. For example, stress can stop periods by preventing ovulation. Stress also affects
sleep and, as a result, reduces Melatonin production.
I N F O R M A T I O N S H E E T Conditions associated with a melatonin imbalance • Abnormal sexual development • Headaches (tension and cluster) • Menstrual irregularities • Cardiovascular disease • Immune disorders • Premature ageing • Cancer • Infertility • Multiple Sclerosis • Delayed sleep phase syndrome • Insomnia • Seasonal Affective Disorder (S.A.D) • Depression • Jet lag • Stress Conditions associated with Cortisol and DHEA imbalance • Allergies • Poor concentration and memory • Asthma • Cancer • Insomnia, depression, • Autoimmune diseases (rheumatoid • Heart disease • Loss of libido arthritis, systemic lupus erythematosus, • Diabetes • Digestive disturbances (diarrhoea, multiple sclerosis, Crohn’s disease, • Impaired immunity/ recurrent infections constipation, bloating, stomach aches/ ulcerative colitis) • Chronic levels of stress • Chronic fatigue syndrome • Osteoporosis How does the test work?
The female Hormone panel measures Progesterone and Oestradiol over 28 days, using 12 saliva samples.
Melatonin, Cortisol, and DHEA are collected using saliva samples in one 24 hour period.
1 - D AY P R O G E S T E R O N E A N D O E S T R O G E N
Hormonal function in women is controlled by the pituitary gland in the brain, which induces hormonalchanges each month and then later during the menopause. Although menopause is a normal part of awoman’s maturation, many individuals experience discomfort due to a decrease in the levels of oestrogenand progesterone. Furthermore, many health practitioners advocate the use of ‘natural’ progesteronecreams, which can rapidly elevate levels of progesterone above normal healthy levels. Symptoms associated with imbalanced progesterone / oestrogen • Menstrual Irregularities • Depression, anxiety • Weight gain, cellulite • Painful, heavy, or irregular periods • Loss of sexual desire • Cancer • Breakthrough bleeding • Endometriosis • Loss of head hair • Osteoporosis • Fibrocystic breast disease • Headaches • Vaginal dryness • Fluid retention and bloating • Dizziness • Night sweats and hot flashes • Infertility • Insomnia • Bladder infections • Ovarian cysts • Loss of energy and enthusiasm • Memory problems, confusion • Premenstrual Syndrome Sample requirements
The test is carried out using a single saliva sample.
Pre Menopause: 1 saliva sample day 21 or Post Menopause: 1 saliva sample any day.
Nationwide Test Kit Service Most of the tests involve simple kits that can be used in your own home. Some may require the help of a nurse or GP. If you cannot
visit the laboratory, you can phone and arrange for your kit to be sent in the post. Once samples have been taken, you simply post the
Test kit back to the laboratory. We would encourage you to use guaranteed delivery and not to send kits over the weekend. For further information consult your practitioner
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