Janet M. Miller, Ph.D. Office Address
Mount Pleasant, MI [email protected] (989)774-2577
Education
Bachelor of Science, 2000, Alma College, Alma, MI
Doctor of Philosophy, 2005, Wayne State University, Detroit, MI
Training 10/2006-present
DNA Sequencing and Analysis Facility Supervisor, Adjunct Assistant Professor, Department of Biology
Central Michigan University, Mt. Pleasant, MI
Postdoctoral Research Fellow, Department of Neurosurgery Wayne State University, Detroit, MI
Other Experience
Research Assistant, Department of Neurosurgery Wayne State University, Detroit, MI
Laboratory Skills
RNA and DNA isolation and purification PCR Agarose gel electrophoresis
Small animal surgery- rodent (neonate and adult), rabbit, feline
- frozen and paraffin sectioning - immunohistochemistry
Primary neuronal cell culture Maintenance and breeding of a specialized rodent colony
Teaching
Teaching Assistant, Physical Therapy Graduate Program-Integrated Physiology PT 5460
Teaching Assistant, Graduate Physiology Laboratory PSL 7040
Biomedical Sciences Program- Physiologic Anatomy BMS 6550 Digestive System, Urinary System (3 hours, 60 students)
Courses at Central Michigan University 2007
Introductory Quantitative Biology BIO 105 (20 students)
Neurosurgery Resident: Bill Underwood MD (5 contact hours/week)
Neurosurgery Resident: John Steele MD (5 contact hours/week)
Undergraduate Students: David Hall, Emma Hostetter (15 contact hours/week) Medical Student: Darlene Johnson (15 contact hours/week)
Research Assistant: Jie Li (10 contact hours/week)
Research Assistant: Kelley Brabant (10 contact hours/week)
Undergraduate Student: Leila Sader (20 contact hours/week)
Undergraduate Student: Alex Shanku (20 contact hours/week)
Undergraduate Student: Carolyn Black (10 contact hours/week)
Undergraduate Student: Amal Anani (20 contact hours/week)
Undergraduate Student: Joel Parraghi (20 contact hours/week)
Undergraduate Student: Shawna Wright (10 contact hours/week)
Brain Awareness Week- invited lecture/demonstration, Grosse Pointe elementary school, Grosse Pointe, MI
Hydrocephalus Association’s 9th National Conference for Individuals, Families and Professionals. Physiology and Anatomy hands on laboratory.
Science, Engineering, and Technology Day, Central Michigan University.
PUBLICATIONS
Original Observations
1. Page AB, Owen CR, Kumar R, Miller JM, Rafols JA, White BC, DeGracia DJ, Krause GS. Persistent
eIF2α(P) is colocalized with cytoplasmic cytochrome c in vulnerable hippocampal neurons after 4 hours of reperfusion following 10-minute complete brain ischemia. Acta Neuropathol (Berl). 2003 Jul;106(1):8-16.
2. Eskandari R, Mcallister JP 2nd, Miller JM, Ding Y, Ham SD, Shearer DM, Way JS. Effects of
hydrocephalus and ventriculoperitoneal shunt therapy on afferent and efferent connections in the feline sensorimotor cortex. J Neurosurg. 2004 Nov;101(2 Suppl):196-210.
3. Miller JM, Kumar R, McAllister JP 2nd, Krause GS. Gene expression analysis of the development of
congenital hydrocephalus in the H-Tx rat. Brain Res. 2006 Feb 23;1075(1):36-47.
4. Miller JM, McAllister JP 2nd. Reduction of Gliosis by Cerebrospinal Fluid Shunting in Experimental
Hydrocephalus. Cerebrospinal Fluid Research, 2007 Jun 7;4(1):5.
5. Li J, McAllister JP 2nd, Shen Y, Wagshul ME., Miller JM., Egnor MR, Johnston MG, Haacke EM, and
Walker ML. Communicating hydrocephalus in adult rats with obstruction of the basal cisterns or the cortical subarachnoid space. Submitted to Experimental Neurology 8-07.
Abstracts
1. McAllister JP II, Eskandari R, Miller JM, Iezzi R, Dawe E, Walraven T, Raza TM, Forman K, Schofding J,
and Abrams GW. Performance and biocompatibility of multiple surface electrodes in cat primary visual cortex. Invest Ophthalmol Vis Sci. 2002;43: E-Abstract 4483.
2. Miller JM, McAllister JP II. Reactive gliosis after short- and long-term shunt recovery periods in
experimental hydrocephalus. Eur J Pediatr Surg. 2003;Dec;13 Suppl 1:Page S53.
3. Shanku AG, Miller JM, McAllister JP II. Progression and reversibility of gliosis due to hydrocephalus in
the H-Tx rat. Cerebrospinal Fluid Res. 2005;2(Suppl 1):S2.
4. Miller JM, McAllister JP II, Krause G. Gene alterations associated with closure of the cerebral aqueduct in
hydrocephalic H-Tx rats. Cerebrospinal Fluid Res. 2005;2(Suppl 1):S4.
5. Nagra G, Li J, McAllister JP 2nd, Miller JM, Wagshul ME, Johnston MG. Lymphatic cerebrospinal fluid
absorption is impaired in a kaolin-induced hydrocephalus model in the rat. Society for Research into Spina Bifida and Hydrocephalus, 51st annual meeting, Heidelberg Germany 2007.
PRESENTATIONS
1. Progression and Reversibility of Reactive Astrocytosis in Experimental Congenital Hydrocephalus.
Poster presentation at the National Neurotrauma Society Symposium 19th Annual Meeting, November 2001.
2. Performance and Biocompatibility of Multiple Surface Electrodes in Cat Primary Visual Cortex.
Poster presentation at Association for Research in Vision and Ophthalmology 74th Annual Meeting, May 2002.
3. Biocompatibility of Multiple Surface Electrodes and Novel Biomaterials in Cat Primary Visual Cortex.
Poster presentation at the Society for Neuroscience 32nd Annual Meeting, November 2002.
4. Reactive Gliosis After Short- and Long-Term Shunt Recovery Periods in Experimental Hydrocephalus.
Poster presentation at Society for Research into Hydrocephalus and Spina Bifida 47th Annual Meeting, July 2003.
5. Experimental Hydrocephalus: Reactive Gliosis After Short- and Long-Term Shunt Recovery. Poster
presentation at the Society for Neuroscience 33rd Annual Meeting, November 2003.
6. Short and Long-Term Shunting Reduces Reactive Astrocytosis In Experimental Hydrocephalus. Oral
presentation at the American Association of Neurological Surgeons and the Congress of Neurological Surgeons, Section of Pediatric Neurological Surgery 32nd Annual Meeting, December 2003.
7. Genetic Influences Driving Closure of the Cerebral Aqueduct in the H-Tx. Rat. Oral presentation at
the pre-meeting of the Society for Research into Hydrocephalus and Spina Bifida 48th Annual Meeting, June 2004.
8. Genetic Influences Driving Closure of the Cerebral Aqueduct in the H-Tx. Rat. Poster presentation at
the Society for Neuroscience 34th Annual Meeting, October 2004.
9. Genetic Influences Driving Closure of the Cerebral Aqueduct in the H-Tx. Rat. Oral presentation at
the American Association of Neurological Surgeons and the Congress of Neurological Surgeons, Section of Pediatric Neurological Surgery 33rd Annual Meeting, December 2004.
10. Gene Expression in Congenital Hydrocephalus and the Subsequent Effects of Gliosis. Oral
presentation at Detroit Medical Center Grand Rounds, Department of Neurosurgery, 2005.
11. Genetic Alterations Associated with Closure of the Cerebral Aqueduct in Hydrocephalic H-Tx Rats.
Oral presentation at Society for Research into Hydrocephalus and Spina Bifida 49th Annual Meeting, June 2005.
12. Progression and reversibility of hydrocephalus induced gliosis in the H-Tx rat. Poster presentation at
the Society for Neuroscience 35th Annual Meeting, November, 2005.
13. Inhibitory Effects of Minocycline on Gliosis in the Hydrocephalic H-Tx Rat. Oral presentation at the
American Association of Neurological Surgeons and the Congress of Neurological Surgeons, Section of Pediatric Neurological Surgery 34th Annual Meeting, December, 2005.
14. Inhibitory Effects of Minocycline on Gliosis in the Hydrocephalic H-Tx rat. Oral presentation at the
pre-meeting of the Society for Research into Hydrocephalus and Spina Bifida 50th Annual Meeting, August, 2006.
15. Inhibitory Effects of Minocycline on Gliosis in the Hydrocephalic H-Tx rat. Oral presentation at
Society for Research into Hydrocephalus and Spina Bifida 50th Annual Meeting, August, 2006.
16. Minocycline Reduces Gliosis and Increases Cortical Thickness in Experimental Hydrocephalus.
Hydrocephalus 2006, Goteburg, Sweden, September, 2006
CERTIFICATIONS
Office of Environmental Health and Safety, Wayne State University
OSHA Laboratory Standard - June 2000 Biosafety and OSHA Bloodborne Pathogens - Annually starting June 2000 Hazardous Waste / Emergency Procedures - Annually starting June 2000 Radiation Safety - June 2000
Division of Laboratory Animal Resources, Wayne State University
Investigating the Mouse and Rat - June 2000 Investigating the Feline - December 2000 Investigating the Rabbit - May 2001 Rodent Surgery Training - February 2003
MEMBERSHIPS
Society of Neuroscience; 2000 - 2006 Association for Research in Vision and Ophthalmology; 2000- 2002
Society for Research into Hydrocephalus and Spina Bifida; 2005- present
Sigma Xi- The Scientific Research Society; 2007- present
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